The aim of the project is a comparative assessment of the combined use of tomotherapy and cellular immunotherapy with a scientific justification of their effect on the tumor microenvironment and changes in the patient's local immunity, as well as the development of optimal conditions for a combination of treatment, which will make it possible to form a powerful immunological weapon against tumor growth and improve the results of lung cancer treatment.
Type of study: monocenter, open.
There are 20 patients in total, including 20 patients with histologically confirmed lung malignancy (small cell/non-small cell carcinoma) no more than 3.0 cm in diameter. The patients will be randomized into 2 groups.
Project participants:
- Marlen Akmyrzauly, the project manager, was dragged
- Askarov Manarbek Bapovich –co-head of the project
- Ganina Anastasia Mikhailovna–biotechnologist
- Batyrbek Nazgul Kayratkyzy–Scientific manager
- Mukhamedzhanova Perizat Myktybekovna–oncologist
- Brimova Aigul Demeugalievna–oncologist
- Larisa Vladimirovna Kozina – Head of the Central Research Laboratory
- Karimova Madina Khamidullievna is a biotechnologist.
Publications on the project: Shayakhmetov T,Bissengalieva V, Orda E,Baiturova S,Berikbol D, Otynshiyev R, Brimova A. Evaluation of positioning accuracy and determination of the optimal margin for the planning target volume during radiation therapy on the Tomotherapy HD system. Onkologia i Radioterapia ( 2023) Volume 17, Issue 9
Director of the Institute of Fundamental and Applied Medicine
Askarov Manarbek Bapovich